Reaktorji za biološka zdravila

Razvoj bioreaktorjev je danes eden pomembnih izzivov pri vzgoji bioloških vzorcev, celic in splošneje v biotehnologiji. V članku so predstavljeni trije glavni tipi reaktorjev, ki se uporabljajo pri procesu pridelave bioloških zdravil. To so mešalni, kolonski in reaktor z dvigovanjem zraka. V prvem delu članka je zajet opis posamezne vrste bioreaktorjev ter kratek opis izdelave bioloških zdravil. V drugem delu je obravnava vloga hidrodinamike pri bioloških procesih, ki potekajo v notranjosti reaktorja.

Reactors for the production of biopharmaceuticals

The development of bioreactors is one of the major challenges in raising biological samples, cells and more generally in biotechnology today. In the article, three main types of biological reactors used in the production of biopharmaceuticals are presented. These are stirred tank, bubble column and airlift reactors. Firstly, the production of biological medicinal products is briefly described, followed by the description of each of the bioreactor types. Further on, the role of hydrodynamics in biological processes that take place inside the reactor is discussed.